Cell-mediated drug delivery

Ultrasound-mediated Drug Delivery

Aptamer mediated niosomal drug delivery

Development of nanoscale carrier systems for targeted drug delivery is crucial for cancer treatment. The current methods of drug delivery exhibit some problems such as lack of therapy efficiency at the desired parts of the body, degradation of the drug before reaching the desired tissue and limitations in cellular penetration. In this work, a novel drug delivery platform was developed to overco...

Peptide-mediated targeted drug delivery.

Targeted drug delivery to specific group of cells offers an attractive strategy to minimize the undesirable side effects and achieve the therapeutic effect with a lower dose. Both linear and cyclic peptides have been explored as trafficking moiety due to ease of synthesis, structural simplicity, and low probability of undesirable immunogenicity. Peptides derived from sequence of cell surface pr...

Ultrasound Mediated Drug Delivery System

Ultrasound has received less attention than other imaging modalities for molecular imaging, but has a number of potential advantages. It is cheap, widely available and portable. Using Doppler methods, flow information can be obtained easily and non-invasively. It is arguably the most physiological modality, able to image structure and function with less sedation than other modalities. This mean...

Surgically Mediated Drug Delivery Techniques

Despite recent insights into the pathobiology underlying central nervous system (CNS) malignant gliomas (MGs) and the development of new putative therapeutic compounds to treat these neoplasms, there remains no curative surgical or medical treatment for these tumors. Extensive surgical resection has been shown to prolong survival but is not a total cure because of widespread infiltrative micros...